I've tried several - forward/reverse, with alternating flow from the pumps worked OK. I have a Gyre 150 (Currently my "Pump A") and a 250.
"Oceanic Gyre" cycle seemed to be simply pushing water - at differing speeds through the day - from both pumps simultaneously. It certainly did help with picking detritus out of the crevices! I found it a bit much in a 65, but will try it again when I move the pumps to the 220.
"Lunar Tidal" cycle didn't seem to work as advertised. The rate of flow changed, but it was all coming from pump "B", with no reversal from pump "A". Again, something I'll have another go at when I move them over.
Currently, they're both set to random-variable flow, with a top speed of 100%. (They're very rarely at that speed, and that not for very long.) Water is gently moving - pretty randomly - in both directions throughout the aquarium.
Looking forward to hearing others' experiences!
~Bruce