24 Hour Praziquantel?

[puccie1]

Have a few new fish in quarantine for several weeks with Copper power, my question is they all seem to be healthy with no signs of parasites or rubbing against stones., was thinking of dosing for 1 day with praziquantel qt tank before putting them in DT tank. Would it make since do it and just for 24 hour period, would the praziquantel be effective for that period.
Thanks

 

[vtecintegra]

If you are treating for flukes, it's recommended to do a second treatment about 7 days later for any eggs that's hatched after the first treatment.

Seems to be a common belief that prazi is effective for about 24 hrs.

I do three treatments.

 

[vetteguy53081]

Have a few new fish in quarantine for several weeks with Copper power, my question is they all seem to be healthy with no signs of parasites or rubbing against stones., was thinking of dosing for 1 day with praziquantel qt tank before putting them in DT tank. Would it make since do it and just for 24 hour period, would the praziquantel be effective for that period.
Thanks

I understand what you’re trying to accomplish
Prazi will lower oxygen and appetite when used t
Not that it will have effect for a one day treatment
Better would be a 60-90 minute bath in ruby rally pro
The bath will address what prazi would Plus velvet, bacterial and more

 

[puccie1]

I understand what you’re trying to accomplish
Prazi will lower oxygen and appetite when used t
Not that it will have effect for a one day treatment
Better would be a 60-90 minute bath in ruby rally pro
The bath will address what prazi would Plus velvet, bacterial and more

Thanks

 

[threebuoys]

Have a few new fish in quarantine for several weeks with Copper power, my question is they all seem to be healthy with no signs of parasites or rubbing against stones., was thinking of dosing for 1 day with praziquantel qt tank before putting them in DT tank. Would it make since do it and just for 24 hour period, would the praziquantel be effective for that period.
Thanks

If you've already followed the 30 day QT copper protocol, I suggest you have a little patience and take a couple more weeks to follow the prazi protocol.

Prazi is only effective against live flukes. The medication causes the live flukes to go into spasms and ultimately detach from the fish and fall to the bottom of the tank. They then starve due to lack of food. If you had flukes in the first place, during the copper treatment they have likely laid eggs either on the fish or on other surfaces in the tank. Those eggs are unaffected by prazi and will ultimately hatch.

It is true that the life of prazi doses diminish over multiple treatments because it feeds bacteria that renders it ineffective. I administer prazi in my QT as soon as I reduce the copper concentration. to between .75 and 1.25 ppm. After 7 days I administer a second dose. After 7 more days I administer a third dose. Then, since the effective life of prazi is very short at that point, I move the fish from QT to DT after 48 hours.

Perhaps I'm overly cautious, but once I move a fish to the DT, I really hate trying to catch it to move it back to QT for something that I might have missed in the first QT treatment.

 

[puccie1]

If you've already followed the 30 day QT copper protocol, I suggest you have a little patience and take a couple more weeks to follow the prazi protocol.

Prazi is only effective against live flukes. The medication causes the live flukes to go into spasms and ultimately detach from the fish and fall to the bottom of the tank. They then starve due to lack of food. If you had flukes in the first place, during the copper treatment they have likely laid eggs either on the fish or on other surfaces in the tank. Those eggs are unaffected by prazi and will ultimately hatch.

It is true that the life of prazi doses diminish over multiple treatments because it feeds bacteria that renders it ineffective. I administer prazi in my QT as soon as I reduce the copper concentration. to between .75 and 1.25 ppm. After 7 days I administer a second dose. After 7 more days I administer a third dose. Then, since the effective life of prazi is very short at that point, I move the fish from QT to DT after 48 hours.

Perhaps I'm overly cautious, but once I move a fish to the DT, I really hate trying to catch it to move it back to QT for something that I might have missed in the first QT treatment.

I guess I was wondering/asking is it necessary to use praziquantel on new fish if there are no signs of fluke,
Thanks

 

[threebuoys]

I guess I was wondering/asking is it necessary to use praziquantel on new fish if there are no signs of fluke,
Thanks

I'm a believer in the QT protocol

Current Quarantine Protocol

2024 Quarantine Procedures Jay Hemdal David Scarborough Protozoans (Cryptocaryon/ich, Amyloodinium/velvet) and Metazoan trematodes/flukes are by far the most common parasites found on newly acquired fish. A carefully managed, proactive quarantine process can effectively eliminate these...

www.reef2reef.com

Flukes are not always immediately evident on a new fish, and prazi treatment is a play it safe option with minimal risk to the fish if instructions are followed. As I said, I don't want to discover I have a problem after I've moved the fish to the DT because they can be very difficult to catch, and even if you catch them, you add a lot of stress to them. But, it's a personal choice.

 

[vtecintegra]

I'm fighting suspected flukes in the DT right now. I was doing 14 days of general cure in QT and it seems to have been ineffective for flukes. Now I'm doing prazi and h2o2 in QT, but it's too late. I've had to catch and treat my hawks, and I've got two grammas that are sick that I got extremely lucky getting out. These things are a big problem once the fish gets into the DT.

 

[puccie1]

I'm fighting suspected flukes in the DT right now. I was doing 14 days of general cure in QT and it seems to have been ineffective for flukes. Now I'm doing prazi and h2o2 in QT, but it's too late. I've had to catch and treat my hawks, and I've got two grammas that are sick that I got extremely lucky getting out. These things are a big problem once the fish gets into the DT.

you probably should dose DT with praziquantel 5-7 interval twice

 

[vtecintegra]

Yeah, currently doing another three round dose of prazi, for the third time. Ready to do an aquabiomics test to see what's in the tank.

 

[Superlightman]

Wich is better praziquantel or rally? Rally seems to be active against more things?

 

[sc50964]

Wich is better praziquantel or rally? Rally seems to be active against more things?

Prazi for sure when it comes to treating flukes

 

[Superlightman]

Prazi for sure when it comes to treating flukes

Where you get this information?

 

[sc50964]

Where you get this information?

personal experience as well as confirmation in that one thread that both of us asked Jay

 

[Superlightman]

I would like to see also other sources

 

[sc50964]

Wich is better praziquantel or rally? Rally seems to be active against more things?

@Jay Hemdal

Do you have other sources that support the use of non-use of this Rally product?

 

[RedoubtReef]

I understand what you’re trying to accomplish
Prazi will lower oxygen and appetite when used t
Not that it will have effect for a one day treatment
Better would be a 60-90 minute bath in ruby rally pro
The bath will address what prazi would Plus velvet, bacterial and more

I thought Hydroplex was what was used for a bath. No? They don't list bath directions for Rally.

 

[vetteguy53081]

@Jay Hemdal

Do you have other sources that support the use of non-use of this Rally product?

I’ve been using 6 years and completely safe and effective
Can’t say the same for hydroelectric and kick ich

 

[vetteguy53081]

I thought Hydroplex was what was used for a bath. No? They don't list bath directions for Rally.

Hyfroplex is a bath but completely ineffective unless your fish have acne which is their main ingredient

 

[Jay Hemdal Verified Community Expert]

@Jay Hemdal

Do you have other sources that support the use of non-use of this Rally product?

The listed ingredients of Rally are: Acriflavine, Aminoacridine, & Formalin. Only formalin has any recent published efficacy against flukes. However, formalin used against flukes is dosed at high levels, as a dip (150 to 167 ppm). That is NOT reef safe, and it is not even fish safe longer than 1 hour. Therefore, the amount of formalin in Rally must be much, much less, and is not effective against flukes. Acriflavine and Aminoacridines are mostly anti-protozoal, they only work against metazoans at very high doses. Ruby Reef says these three ingredients are synergistic - but I have no published evidence of that. I try VERY hard to only recommend medications that I have solid published references for.

Does this make sense: it is not my responsibility to prove that this product works, that is the responsibility of the company marketing it. There are no independent published reports that I've seen that show that its ingredients works against flukes at reef safe levels.

Jay