Almost any layer based construction isn't going to be watertight. There can be issues with water absorption, but bubbles from printing (just from humidity in the filament) or other extrusion irregularities would create small leaks in the part - and thanks to capillary action, any tiny hole would wick liquid away continuously.
An alternative is post processing, but you could also just coat it with something - a sealer used for other porous materials would work just fine and there should be plenty of options. Even something as simple as a plastic bag could do the job provided it didn't have a hole, you really just need a barrier.