I just came back to the thread to ask the same question. I’m guessing I’ll need to do a massive water change after treatment is over. The skimmer is still unable to collect anything unless I put it on a stand and have the pump barely in the water. It’s been 4 days.
A few notes on my experience so far for anyone trying to decide on the product:
There has been a slight increase in alkalinity, and I have lowered my dose from 165 to 150mls (based off trident and manually adjusting the DOS). Alk has gone from 8.5 to 9 (whereas it is usually 8.4-8.7), but the calcium has been relatively the same. I know it’s not a huge difference, but it is definitely a change due to using the product...either directly or indirectly. I took the co2 scrubber offline because the mass skimmer overflow in combination with the scrubber puts me over 8.5ph around 7pm (it is usually between 8.2-8.4pH and it’s never hit 8.5) The rise in pH may be the culprit for the alk increase. (Yes I know the opposite should happen, and this change is very very minimal, but I’m just saying the pH increase is certainly a part of the differential diagnosis.)
As far as the corals are concerned, a few LPS have reacted negatively. A have a super sensitive little brat of a Duncan that closes at the slightest bit of change, and it has been closed up since 24 hours in to treatment. Also, my torch garden has acted a little bit negatively but nothing major. Again, these changes could also be due to micro bubbles and higher than normal pH. I changed the filter sock at about 48 hours into treatment, and it was slammed full of crap. I couldn’t tell if it was all dead flatworms or just gunk from the “unintentional mild bubble scrubbing”. Either way, it 100% was not a normal 2 day old filter sock. And most importantly, zero negative reactions to anything else. Fish are normal and all other corals are normal. The acros have PE but they also had PE before treatment, likely due to a consistent daily dose of FWS for about 6 months....but the aefws were still present. I saw this product and wanted to give it a chance! I’ll update if anything changes or I’ll update after treatment if all goes well until then.