The ones in the sand are the easiest, just scoop them out. Be careful if you use Aptasia-X. It does work but you need to be able to get the whole aptasia or they will spread like what happened in my tank. It killed the ones that were out on top of the rock, but the ones in the holes and crevices you think you got but days later they come back in numbers. My tank is infested now and I added some Berghia Nudibranch a couple of weeks ago hoping they take care of the problem.