Antibiotics ???

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I read that it is recommended to use Kanaplex, Metroplex, and Furan-2. (the trifecta) Are thses meds any better or worse than Maracyn and Maracyn-2? I'm not trying to get into a brand battle. But I see that Maracyn is minocycline (gram negative) and Maracyn-2 is erythromycin (gram positive). I know both of those to be very good antibiotics from a human standpoint. What is the best route for the life of my fish?

@Humblefish
@melypr1985
 
It depends on the infection and the fish. You don't always need to use the entire trifecta and the trifecta doesn't always work. sine it's difficult to determine which exact bacteria you are dealing with you have to kind of try antibiotics until one works. If the trifecta doesn't work, then you my switch to the Maracyns or even the Sulfas. I'm more familiar with the trifecta meds though and have more experience with them. I tend to stick with them unless the infection doesn't respond to them.
 
I'm referring to broadest spectrum. Trying to stock up before a big order of fish. No infection in particular


Which meds are you referring to with the sulfas? I can get plenty of sulfas, not necessarily in fish form though.... Id have to guess dosages
 
IMO & E

Kanaplex + Furan-2 + Metroplex offers the broadest spectrum of treatment.

Maracyn 1 & 2 are also full spectrum but not as fast acting as the trifecta. However, the Maracyns are gentler on the fish than the trifecta.

FWIW; this is the antibiotic I have my eye on as my new go-to once I can resume testing: http://store.nationalfishpharm.com/Nitrofuracin-Green-59584.Item.html

Initial results were amazing, but I only tested for 6 months on 8 fish with really bad infections. Saved 6, lost 2. And all 6 were rehomed and are still doing great (I check). ;)
 
I went with the trifecta because I was able to get my hands on it quickly when I needed it. The nitrofuracin green would be easier to apply, since you only have one medication to dose vs. three.
 
If you could do either option would it be the nitrofurican green or the kanaplex/metroplex/furan-2?

Both are wide spectrum, capable antibiotic concoctions. But if I could only choose 1 for my fish medicine cabinet, it would be NFG.
 
Should NFG or kanaplex/metroplex/furan-2 be used prophylactically to treat incoming fish? If so, what types of fish?

No, you should not treat with antibiotics prophylactically (besides maybe metroplex for brook/uronema if you are using copper vs. CP)

Antibiotics don't "cure" fish, but rather keep bacteria populations in check until the fishes immune system can recover and handle the infection on its own.

As with humans, improper antibiotic usage can result in resistant bacteria. If a fish becomes sick or injured down the line and develops an infection, the antibiotics might no longer work.

You should only treat if you observe signs of infection.
 
Should NFG or kanaplex/metroplex/furan-2 be used prophylactically to treat incoming fish? If so, what types of fish?

IMO no; antibiotics are too harsh to be used on fish prophylactically. Best to wait until visible symptoms (cuts/injury, white patches, red streaks) first present themselves. The reason most people lose fish to a bacterial infection is because:
  1. The infection is "secondary" to a preexisting parasitic or worm infestation. Many times it's the infection which kills the fish, not the parasite/worm. Having to fight both simultaneously puts the fish's natural immune system and the hobbyist trying to treat at a serious disadvantage (more on that here). The odds of successfully treating a bacterial infection are far greater IF a parasite/worm is not also in play. Proper QT helps ensure that the fish only encounters a "simple" gram positive infection in the DT; which is sometimes curable just by soaking vitamins in fish food.
  2. However, sometimes a fish's immune system still needs a helping hand (like our own bodies). When this happens, it is imperative to have antibiotics on hand to begin treatment ASAP. If you have to wait to order them off of Amazon, it may be too late by the time they finally arrive. :(
 
Thanks for the quick responses guys!

Antibiotics don't "cure" fish, but rather keep bacteria populations in check until the fishes immune system can recover and handle the infection on its own.

As with humans, improper antibiotic usage can result in resistant bacteria. If a fish becomes sick or injured down the line and develops an infection, the antibiotics might no longer work.

I feel these two statements contradict each other. Now, I may be way off base here; but my understanding was that antibiotic resistance develops due to the bacteria changing in some way to be come resistant. For example, this could occur if the antibiotic course was cut short (i.e. ended early); thus there are still some bacteria present which can mutate and become resistant.

This would mean the antibiotic needs to remain present until the fish is cured, and not just used to keep bacteria populations in check...

IMO no; antibiotics are too harsh to be used on fish prophylactically. Best to wait until visible symptoms (cuts/injury, white patches, red streaks) first present themselves. The reason most people lose fish to a bacterial infection is because:
  1. The infection is "secondary" to a preexisting parasitic or worm infestation. Many times it's the infection which kills the fish, not the parasite/worm. Having to fight both simultaneously puts the fish's natural immune system and the hobbyist trying to treat at a serious disadvantage (more on that here). The odds of successfully treating a bacterial infection are far greater IF a parasite/worm is not also in play. Proper QT helps ensure that the fish only encounters a "simple" gram positive infection in the DT; which is sometimes curable just by soaking vitamins in fish food.
This is how I have used these medications in the past, although I stock all three, but have not used them all at once (with minimal success I might add). So, from my own anecdotal observations, I either used the wrong meds, waited too long or there was another underlying problem. I should also add that I am not a fan of any prophylactic treatment, however I am coming around to it being needed in some cases (*cough* depending on where I buy the fish)...

I am trying to understand what actual advice is being given in this thread. It seems logical to stock all the six main products mentioned in this thread and treat accordingly. But then again, I suppose the problem we encounter as hobbyists is being able to accurately identify the disease in a timely fashion; hence needing to use "the trifecta" as a blanket.

Now, going back to NFG as an alternative for "the trifecta" (sorry, I just like saying that in my head, lol), is it also effective against some fungal and parasitical infections, or is it used strictly for bacterial infections? (I am thinking about Metroplex's claims here, however legitimate they may or may not be)...
 
Now, going back to NFG as an alternative for "the trifecta" (sorry, I just like saying that in my head, lol), is it also effective against some fungal and parasitical infections, or is it used strictly for bacterial infections? (I am thinking about Metroplex's claims here, however legitimate they may or may not be)...

Well, NFG contains methylene blue which may have some antiparasitic properties. IME; not enough for complete eradication though.

This provides a rundown of all the benefits of MB: http://www.americanaquariumproducts.com/AquariumMedication3.html#methylene_blue

The other two ingredients found in NFG, Nitrofurazone and Sulfathiazole, are well-known antibiotics.

Can NFG be used in conjunction with CP or copper?

Yes to both
 

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