It's correlated to something though, even if you can't see what it is. Corals don't die for no reason.
Flow is the most transparent parameter, so I'd consider unseen changes to flow as the #1 suspect.
Something upstream that blocked flow most likely: maybe one or more corals growing out or that have been added, maybe even a pump problem or delayed maintenance just reducing overall flow. This throws all borderline flow areas into problem status if it happens. And it's not easy to see – we're not talking about a dead zone of no flow. Just where flow has gone from adequate to inadequate.
Other things can happen too.
Maintaining a low-nutrient system might make this more likely as you end up messing with the coral's phosphate supply.
Borderline flow combined with borderline nutrient availability gives you a potential for problems like this. Most folks aren't thinking too much about phosphate requirements these days just "nutrient eradication"....that can be tough on corals, especially in some circumstances.