No. You want the skimmer to remove the wastes, excess food, organics and stuff from the water so you want to skim from the overflow or early in the sump, not the return.
It wouldn't be nearly as efficient. Its best to match your return pumps flow to your skimmer flow and place the skimmer where it receives the overflow water or is even fed by gravity from the oveflow and use a needlewheel or mesh impeller to whip it into a froth.