API general cure only or with metro?

[ap7x]

What does dosing metroplex with general cure cover that only general cure doesn’t for
prophylactic treatment?

So general cure then metro in between doses vs just general cure? Or is it redundant?

Thank you!

 

[User]

A bit redundant

Metroplex is metronidazole

General cure is metronidazole plus praziquantel.

 

[EmdeReef]

API General cure already contains metro, no need to dose additional metro.

 

[ap7x]

Ok thanks bc I saw one suggestion of general cure + metro in between for brook/Uronema but I thought general cure covered those already?

Just checking whether additional metro treats something general cure only misses... since metro is every 48 hr dose

 

[Big G]

Sometimes we dose General Cure into the water column, and then feed the fish Metro + Focus to work on stubborn internal parasites. Prazi usually works best being absorbed through the skin; whereas Metro usually works best ingested directly into the gut.

 

[ap7x]

Ok I ended up finding one reply by humble:

Two proactive methods for treating ich + velvet + brook + uronema are as follows:

1. Chloroquine phosphate
2. Combining copper + metronidazole

If using API General Cure with copper, just substitute your first & last metro treatment for GC. (Since GC already contains metro, you want to avoid overdosing by only using Metroplex or straight metronidazole powder 48 hrs before or after GC.) Treatment regimen would go like this:

Day 1 - Dose General Cure
Day 3 - Dose metro
Day 5 - Dose metro
Day 7 - Dose General Cure
Day 9 - Dose metro (probably optional at this point)

^^ That will deworm a fish + effectively treat for brook & uronema. Add copper to the above, and you're also prophylactically treating for ich + velvet.

Seems to imply the extra metro doses are needed to prophylatically cover brook and Uronema?

 

[rkpetersen]

What humble is basically saying there is that you shouldn't just use GC in this protocol because to do so would result in an overdose of the other ingredient in GG, praziquantel. Thus metro only except on the two days when you would want to dose prazi. Metro every 48 hours is recommended for brook, after initial treatment.

 

[ap7x]

Right so basically going back to the original question - general cure alone isn’t good enough for brook? Need to add metro every 48 hrs as well?

 

[4FordFamily]

Right so basically going back to the original question - general cure alone isn’t good enough for brook? Need to add metro every 48 hrs as well?

Metro every 48 much more effective against brook and uronema.

I feed GC. Dosing it for flukes in metro is generally OK as fish can handle double dose of metro but I’d use prazi.

 

[GoldeneyeRet]

Metro needs to be dosed every 48 hours to cover uronema and brook.

Prazi needs to be dosed once to kill flukes and again 5 to 7 days later to kill newly hatched eggs.

Dosing gc every 48 hours will be wasteful and unduly harsh on the fish.

Dosing only gc 5 to 7 days apart wont treat brook ir uronema.

Using gc for first and 4 th dose and metro only for the rest covers all three parasites as efficiently and safely as possible with these meds.

 

[ap7x]

Yup, wouldn’t have dosed gc every 2 days but I thought gc alone covered brook+uronema. Which was why I asked if gc alone covers everything or if I needed metro in between.

Glad I checked lol thanks all!

 

[Fastpitch]

What humble is basically saying there is that you shouldn't just use GC in this protocol because to do so would result in an overdose of the other ingredient in GG, praziquantel. Thus metro only except on the two days when you would want to dose prazi. Metro every 48 hours is recommended for brook, after initial treatment.

Looking back, I think this is how I lost my last two fish in QT to uronema. I was using GC 5 days apart and not dosing metro in between.

 

[ttnguyen98]

Can you please clarify the treatment again ?
Day 1- dose API general cure
Day 3 - dose metroplex
Day 5- dose metroplex
Day 7- dose API general cure
Day 9 dose metroplex (optional)
What day does humble recommend to add copper (Cupramine, I suppose) to the above schedule to treat for ick? I am confused.

I thought that metronidazole contained in Metroplex treats ick, and marine velvet already. Why need the additional copper treatment?
Thanks for your help.

Ok I ended up finding one reply by humble:

Two proactive methods for treating ich + velvet + brook + uronema are as follows:

1. Chloroquine phosphate
2. Combining copper + metronidazole

If using API General Cure with copper, just substitute your first & last metro treatment for GC. (Since GC already contains metro, you want to avoid overdosing by only using Metroplex or straight metronidazole powder 48 hrs before or after GC.) Treatment regimen would go like this:

Day 1 - Dose General Cure
Day 3 - Dose metro
Day 5 - Dose metro
Day 7 - Dose General Cure
Day 9 - Dose metro (probably optional at this point)

^^ That will deworm a fish + effectively treat for brook & uronema. Add copper to the above, and you're also prophylactically treating for ich + velvet.

Seems to imply the extra metro doses are needed to prophylatically cover brook and Uronema?

cle

 

[ngoodermuth]

Can you please clarify the treatment again ?
Day 1- dose API general cure
Day 3 - dose metroplex
Day 5- dose metroplex
Day 7- dose API general cure
Day 9 dose metroplex (optional)
What day does humble recommend to add copper (Cupramine, I suppose) to the above schedule to treat for ick? I am confused.

I thought that metronidazole contained in Metroplex treats ick, and marine velvet already. Why need the additional copper treatment?
Thanks for your help.


cle

Nope, metronidazole alone has not been proven to treat ich and velvet. You can use the copper while using the above schedule, I usually ramp up to therapeutic over 3-4 days. Then you just have to hold the correct level for 14 days (if using a second sterile QT) or 30 days if only using one tank. For cupramine, that is .5 (measured with the seachem test kit or hanna checker). If you do a water change, just dose the clean water before it hits the tank to match the level in your QT.

 

[ngoodermuth]

Personally, I use the two QT method for copper, and save the prazi for after copper/metro (unless absolutely necessary for active fluke infestation confirmed by freshwater dip) So, I'll run copper/metro together for 14 days. Transfer to second QT and do two doses of prazipro 5-7 days apart, while feeding GC+focus soaked food.

This schedule covers: velvet, ich, brook, uronema, flukes, and both intestinal worms/flagellates. Bacterial issues I'll treat as they pop-up.

 

[ttnguyen98]

FYI.
Metro+ Cupramine for treatment of parasites (ick, brooks etc...) is too harsh on fish per Seachem comments.

 

[ngoodermuth]

Hmm...I’ve used metro and cupramine together many times, as have many others here with no ill effect. I feel like maybe the customer service representative is required to give more of a “cover your butt” blanket response regarding mixing medications, in general.

 

[User]

Hmm...I’ve used metro and cupramine together many times, as have many others here with no ill effect. I feel like maybe the customer service representative is required to give more of a “cover your butt” blanket response regarding mixing medications, in general.

Exactly right.

 

[Big G]

Hmm...I’ve used metro and cupramine together many times, as have many others here with no ill effect. I feel like maybe the customer service representative is required to give more of a “cover your butt” blanket response regarding mixing medications, in general.

+1 They, Seachem, have posted several responses that made me think the same thing.

 

[ttnguyen98]

Personally, I use the two QT method for copper, and save the prazi for after copper/metro (unless absolutely necessary for active fluke infestation confirmed by freshwater dip) So, I'll run copper/metro together for 14 days. Transfer to second QT and do two doses of prazipro 5-7 days apart, while feeding GC+focus soaked food.

This schedule covers: velvet, ich, brook, uronema, flukes, and both intestinal worms/flagellates. Bacterial issues I'll treat as they pop-up.

I have 2 new fish ( blonde Naso and Carpenter flasher wrasse) bought from Liveaquarium going to a 10 gal Quarantined tank. My treatment schedule is as follows:
Day 1: API general cure
Day 3: cupramine (half dose only)
Day 5: cupramine (half dose only)
Day 7: API general cure (final dosing)
Day 9/11/13/15: cupramine (half dose)

The above schedule will deworm the 2 fish and treat ick and marine velvet for 14 days of copper treatment. Also do 10% water change every 4th day.

On day 1, I did a 2 minute freshwater dip ( matching pH and temperature levels) prior to transferring to QT. Notice some dead milkyish worms (look like a bergudia nudibranch) at the bottom of the glass jar.

Now 24 hr progress in qr with General Cure (GC) treatment. My Naso Tang seems like getting both skin flukes and gill flukes (white colored patches) on its body. See attached pictures. Also, kinda after the fact that the GC dosage is too strong for the wrasse after I read up some other threads from reef2reef.

1) Can someone please identify or confirm the white colored patches on the Naso Tang? Andany advise on the wrasse? Shound I take the wrasse out of the qt, etc...?

2) Do I feed or starve the fish during the 2 days of GC treatment?
Thanks in advance for for all comments and inputs