Theoretically one could run a bacteria free tank, if they could manage the ammonia created. Growing plants hydroponically is similar, some people introduce beneficial bacteria to aid growth, while other methods kill all bacteria in order to control the exact nutrients delivered. Obviously in an aquarium bacteria plays a major roll, but adding bacteria just to add it can’t be efficient. If a certain bacteria doesn’t find food and a place to exist it’ll just die. I figure the bacteria that finds it’s way into my tank via frags, fish, live rock etc and survives and grows are the only bacteria I need. And let’s not forget the bacteria and microbes that live all around us, all the time will also find it’s way into our tanks.