I'm no expert with macros, but have some experience with common species.
With lighting, it depends on what kind of macros you're focusing on - most greens will be from shallower waters, and will look and grow best under daylight-ish lighting (think freshwater planted tank lights, or around 6500K). Most reds are from slightly deeper waters, and do a bit better with more blue lighting (around 10000K). Browns kinda fall in the with the green macros, so you'd want some daylight lighting with maybe some actinics for the blue sheen that some of them get. I recommend you look into either a LED fixture made for a freshwater planted tank, DIY yourself a fixture, or look into a T5 fixture and just make use of mainly 6500-10000K bulbs. Correct me if I'm wrong, but it's what I'd do.
For flow, I think you'll usually want as much flow on a macro as you can get without causing them to fall apart. My dragon's breath was growing quite a bit when it was a few inches in front of my Koralia 425 in a 10 gallon, but it ended up falling apart due to the flow. I'd say shoot for relatively swift flow across the entire tank, and try your best to avoid dead spots.
Detritus and mulm will build up on most macros, and you'll have to do your best to keep them clean - having higher flow will help with that.