I just started dosing it in my system as of 4/11/17. i mixed in 100 pills just the powder ofcorse, in to my 1000 gallons of water volume. I ordered another 100 pills just in case i may need to dose more later on. so far im seeing a little curling on the ends of some batches and a littler lighter green color as well. i was going to siphon out first everything then dose, but i figured i wont be able to see the results if i do that so i just dosed like everyone else without siphoning. sps still look great , fish are fine and no problem with the inverts. ill keep an eye on my dragons breath algae and my cheato to see if it stunts its growth or has any impact on it as well.