FWIW the 1st time I dosed 10mg per gallon a week apart totaling the recommended dosage of 20 mg per gallon. It worked on all of the bryopsis and hair algae but it took 4~5 weeks total. I waited another 2 weeks before I added a skimmer (I don't normally run a skimmer in this system) and carbon to remove the Fluconazole. In the following 10 days afterwards, the algae came back in force worst than before.
On go around two, I started again with the half dose of 10 mg per gallon and dosed 3x over three weeks. Again, it took quite some time (4~5 weeks), not like the couple of days that were read for some. This time around though, I have not actively taken any of the Fluconazole out either by using carbon, skimmer or water changes. My system has had the Fluconazole in without active removal since Columbus day without any adverse effects on clams, SPS, zoas, leather, lobo & gorgonian.