agreed they're bulletproof. I wonder if their ich is able to transmit into marine systems though? not sure how ich works in varying saline environs
in our cycling thread as of a couple years now we list only three conditions which will kill off tank bacteria to the point you can measure the loss with an accurate ammonia test kit (where after event X, the water is changed and the substrates in question can no longer oxidize 1 ppm ammonia in 24 hours):
-true drying, verified drying of all surfaces internal and external on a given substrate can kill nitrifiers who are housed alongside non nitrifiers in insulating scums;
-obvious medication events, that directly target gram neg bac or general bac communities through some mechanism
-temp extremes so severe and sustained an aquarium is never likely to see them. no heater malfunction that kills a whole tank of coral will kill off the nitrifiers. it takes something bigtime, and sustained. Dieoff from a heater malfunction will increase tank nitrifiers due to a huge temp new food source of rot from dying organisms who had tighter temp requirements than our bac, and because that temp spike will still be within the temp-influenced reproduction activity for general aerobic bac who just got lots of rare food input.
we never did list changes in salinity as a sterilizing agent this thread was a neat confirmation with that little info snippet above.