I voted maybe, but only because of the not sure part added to the maybe. It can benefit aquariums sometimes. Right now I am dealing with Dino's.
Thinking now, I will change my vote to No. I would never turn off my skimmer. Why would you? The question as to why you would turn off your skimmer needs to be asked. Is it to raise N03 and P04? I will change my vote to No for that exact question I asked myself and already know the answer to. The amount of oxygen added to the tank thru skimming is priceless, so why would you turn it off. Again, I am going thru a Dino's issues and needed to raise my N03 and P04 from 0,0. I didn't turn off my skimmer, I just simply removed the plug and allowed it to dump back into the tank.