I'm about to the point of liquid dosing vinegar or vodka. Because i been running reactor with npx bio pellets and I've seen no change at all in over a month.
I had zero luck with bio pellets in several reactors despite trying for well over a year, so I'm not convinced they really work (or if they do, it seems to be an insignificant amount).
My setup (nitrates between 3-5ppm and phosphates between 0.01-0.025ppm):
Red Sea Reefer 750XXL (mixed reef, 31 fish, well over 100 inverts)
* 4x 100-micron sock filters (changed out every 2 days)
* Nyos Quantum 160 skimmer (emptied every 3-4 days)
* Nyos Torq Reactor 1: 2.0L Nyos Zeo (changed every 2-4 months)
* Nyos Torq Reactor 2: 1.0L Nyos Carbon/Phosi-Ex (changed every 1-2 months)
* 2x MarinePure 8x4x4 bio media blocks
* 2x boxes of MarinePure 1.5" bio spheres
* 2.5ml Nyos Zero daily
That's it. No refugium, algae scrubber or any other equipment other than a 57-watt AquaUV.