Chemiclean didn’t work on Cyano

My other option is Azithromycin which I heard can be effective. But I don’t want to keep treating the tank with antibiotics.
I wasn't saying your cyano is resistant, but that it IS occurring. Can you just wait it out? Sometimes patience is the only intervention needed...
 
IME I broke out in cyano when my phosphates were high relative to my nitrates. Increasing my nitrates by adding more fish and running my skimmer part time, along with manual removal and better flow made my cyano disappear . . . in time. ‘In time’ are the keywords. You can’t expect it to go away overnight.
 

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