I have searched R2R threads and cannot find a comment on this. The Diamondback site (source of CP) has a page that states that when using CP, the salinity should not be above 14 ppt to be most effective. That is basically hypo levels, I think. They sell the medication so they likely know what they are talking about, but I have not seen this stated elsewhere (but may have missed it)
Their quoted treatment protocol is different as well from the one-time 40-60 mg per gallon for thirty days typically referenced here on R2R. If my math is right, they are saying 19-38mg per gallon every five days for four treatments. That would end in a concentration of 76-152mg/gallon (but maybe there is loss of medication somehow along the way?).
Any thoughts/experience on the effectiveness of CP at other levels of salinity? I would greatly appreciate any input on this or the Diamondback treatment protocol.
Thanks,
Mark
From the Diamondback Site:
Treating Cryptocaryon With Chloroquine
Chloroquine is an effective treatment for Cryptocaryon, as it is non-toxic to fish and the natural bacteria of the aquarium, but highly toxic to algae and some invertebrates. It is shown to be most effective when used in conjunction with hyposalinity, or reduced salinity of the water.
The typical treatment involves adding five to ten milligrams of Chloroquine per liter of water every five days for a minimum of four treatments. However, your veterinarian or aquarium specialist will provide more detailed instructions for treating your unique case.
Chloroquine Considerations
When using Chloroquine to treat fish afflicted with Cryptocaryon, the sick fish should be removed from the aquarium and placed in a quarantine tank. The water’s salinity level should be maintained under 14ppt, and the tank light should be left off during treatment.
Their quoted treatment protocol is different as well from the one-time 40-60 mg per gallon for thirty days typically referenced here on R2R. If my math is right, they are saying 19-38mg per gallon every five days for four treatments. That would end in a concentration of 76-152mg/gallon (but maybe there is loss of medication somehow along the way?).
Any thoughts/experience on the effectiveness of CP at other levels of salinity? I would greatly appreciate any input on this or the Diamondback treatment protocol.
Thanks,
Mark
From the Diamondback Site:
Treating Cryptocaryon With Chloroquine
Chloroquine is an effective treatment for Cryptocaryon, as it is non-toxic to fish and the natural bacteria of the aquarium, but highly toxic to algae and some invertebrates. It is shown to be most effective when used in conjunction with hyposalinity, or reduced salinity of the water.
The typical treatment involves adding five to ten milligrams of Chloroquine per liter of water every five days for a minimum of four treatments. However, your veterinarian or aquarium specialist will provide more detailed instructions for treating your unique case.
Chloroquine Considerations
When using Chloroquine to treat fish afflicted with Cryptocaryon, the sick fish should be removed from the aquarium and placed in a quarantine tank. The water’s salinity level should be maintained under 14ppt, and the tank light should be left off during treatment.

