Chloroquine Phosphate withdrawal?

[I_Got_Crabs]

I had 3 fish in a 20 gal QT dosed with Chloroquine Phosphate for 4 weeks.

Yesterday, I did a 100% water change, so that I could do a course of prazipro. Today, two of the fish (midas blenny and allens damsel) actually seem a little happier and more active than usual, but my Royal Gramma is lethargic and disoriented, floating upright on the bottom and breathing a little heavier than usual. Up until today he was eating like a pig but now he is not eating at all. There are no visible dots or external signs of disease.

The only things that changed were 1) removal of Chloroquine Phosphate, 2) 100% water change. I acclimated them for 30 mins but the new water has a salinity of 1.023 and a ph of 8.2 while the old water had 1.027 and 7.9.

Any ideas what could have done this, or what to look for to start ruling things out?

Thanks in advance.

 

[DLHDesign]

I'd guess it's just the shock of the change over. You didn't mention it, but how close were the temps on the tanks?

 

[HotRocks]

I had 3 fish in a 20 gal QT dosed with Chloroquine Phosphate for 4 weeks.

Yesterday, I did a 100% water change, so that I could do a course of prazipro. Today, two of the fish (midas blenny and allens damsel) actually seem a little happier and more active than usual, but my Royal Gramma is lethargic and disoriented, floating upright on the bottom and breathing a little heavier than usual. Up until today he was eating like a pig. There are no visible dots or external signs of disease.

The only things that changed were 1) removal of Chloroquine Phosphate, 2) 100% water change. I acclimated them for 30 mins but the new water has a salinity of 1.023 and a ph of 8.2 while the old water had 1.027 and 7.9.

Any ideas what could have done this, or what to look for to start ruling things out?

Thanks in advance.

Have you treated for any other ailments?

Fed med soaked foods? Dewormed? Anything like that?

CP can supress bot not eliminate other things such as flukes. So it's possible something else is afflicting the fish and now becoming a problem.

 

[I_Got_Crabs]

I'd guess it's just the shock of the change over. You didn't mention it, but how close were the temps on the tanks?

The temps went from 78 to 80 with 30 min acclimation.

 

[I_Got_Crabs]

Have you treated for any other ailments?

Fed med soaked foods? Dewormed? Anything like that?

CP can supress bot not eliminate other things such as flukes. So it's possible something else is afflicting the fish and now becoming a problem.

CP was all I dosed. I was planning to do prazi pro bath and metroplex in food to treat for potential flukes. Think I should start that?

 

[I_Got_Crabs]

CP can supress bot not eliminate other things such as flukes. So it's possible something else is afflicting the fish and now becoming a problem.

Update:

I suspect that this was the case. The royal gramma has improved since I dosed prazi pro, and is now eating again.