How do I treat? The metroplex and kanoplex isn't working
Thank you for posting additional pics. There is a toss up here. The previous pics showed what looked like warts and suggested an internal issue. I just viewed you two new pics and this may not be a disease but part of fishes' anatomy. To clarify this appearance is not normal but is a trigger from the fish.
I sold these at my LFS and often wondered why they were even sold as few hold up well. As you notice, they are very slow swimmers, yet need food source regularly. Often when annoyed by tankmates in which they should not have many, they can emit a secretion.
Where does secretion come from? . . . . . . if you look at their bodies with a magnifier, their skin has a series of hexagonal-shaped dermal plates that are fused together and when scared or annoyed release this mucus often called a toxin but there are FEW cases of any toxic poison released by them. These little plates expand which I believe is what you are seeing and not an infection. THIS IS A THEORY AND NOT A COMPLETE ANSWER but explains why they are present.
Have you noticed fish hovering around this fish or snatching food it is trying to get to?
Is fish eating ? If so- what foods?
Are you running carbon ? If not - Add some as it will reduce any levels of toxin if Present.
What is your current ammonia and nitrate level?
There is bacterial mass around its horns and you can continue kanaplex but pull off from metroplex