Well, for background, if it makes any difference, I have never let nutients totally bottom out. Close, but never zero. Phosphates have been between .05 and .1 and I HAD been keeping nitrates around 3. Since this outbreak I have increased my NeoNitro dosing and am maintaining between 10 and 15 now on Nitrates. I also have added a ton of copopods and amphipods, almost since the beginning, and have added live phyto on a regular basis since then. 165g total volume. Salinity steady at 34.8 ppm, Alk 8.2, (dose Fusion 2 part) Cal 500. Prob 10-15 small frags, 10-12 fish, big CUC, refugium full of rubble rock. 20 % wc every 2 weeks. Here's what changed and what I suspect may be the cause. : I started adding adding 5 ml KZ FlatwormStop daily about 3 weeks prior to emergence of the orange patchs on the sandbed. I stopped as soon as I noticed in case it was the cause.