With a scrubber as the algae grows the water flow changes and you are always dealing with a water fall sound, or in an upflow design clogs and escaping bubbles. Cleaning is just a chore. The flow you will always be adjusting, with the water fall type you will get the gurgling sound at irregular intervals. Look around at any swap meet or craigslist and you will find these abound,
I run reactors on all my tanks. With quick disconnects it is easy and clean to maintain, when dialed in you will usually harvest about once a month. Dropping a pump in the back chamber is just no big deal, it just flows through the reactor and back into chamber 3. You are talking about flow, there is no pressure, so plumbing is simple and should be foolproof. Trying to put a scrubber back there I guarantee you will have flow issues. And to use an upflow scrubber inside the display takes up valuable real estate and is unsightly.
I was already running reactors and because of all the rage, I tried a scrubber. I did a diy santa monica knockoff in my biocube and a waterfall type on a 180. I've seen the real Santa Monicas in action, and all of the more known water fall type scrubbers. They all have the negatives I spoke of, it;s just a matter of choosing your poison. Scrubbers are not for me and alot of people that I know. All of my friends have scraped theirs as well.
An added plus, I fill my reactors with a mixture of macros, and harvest the fern caulerpa and gracillaria for my angels and tangs.