They absolutely work. There are several factors at play though. Here are a few:
1)Skimmer intake (usually given as liters per hour)
The higher the skimmer intake, the more air pulled through the media per given amount of time. The equates to more CO2 scrubber as well as faster consumption of the media.
2)Air exchange with the room
If you have a lot of surface agitation and air movement you are increasing the exposure of your tank to the high levels of CO2 in your home. The more this happens, the lower the pH of your tank.
I've found a method that works REALLY well for me. I use a lifereef skimmer which recirculates air from the skimmate cup into the venturi intake. Lifereef is designed like this to keep the venturi in a humid environment to prevent clogging with salt creep. I placed my media right in this recirculation so that the media is fed the humid air from the skimmate cup. This makes it so theoretically you are having to scrub way less CO2 since you are only pull the CO2 that is in skimmer vs constantly pulling high CO2 room air. I have noticed a HUGE decrease in media use this way. The second benefit is that CO2 media gets exhausted wayyyy faster when it's dry, so you are always keeping it humid in there with this method.