Diet, size, special needs, etc.
They get pretty massive, as national aquarium pointed out they keep them in more cold water with lower salinity, and they spend a lot of time foraging what's in the sand constantly, which depletes really fast. While it may seem like they eat whatever meat falls to the bottom, they're not actually fully satisfying their needs from that, it was once thought they exclusively fed on worms and living fauna in the sand but I think national aquarium and some research facilities disproved that.
They're basically the same issue as sandsifting starfish where they just cannot get enough even with the supplemental feeding since they deplete it so fast especially as they grow.
In
theory you might be able to keep them with a dedicated design for them, in the parameters that anything else wouldn't thrive well in, but the diet is still something everyone is figuring out. Even the labs trying to aquaculture them haven't been successful with their eggs (horseshoe crabs are usually found on beaches for this) and the one site I found on them come up with some kind of in-house food with gelatin to try and give them everything.
Horseshoe crab (HSC) hemolymph is the source of Limulus amebocyte lysate (LAL), a critical component in sterility testing that ensures drug and medical devic...
www.frontiersin.org
Most of the time when you hear of horseshoe crab successes within the hobby, its someone with a really large well established setup going on a couple years or they speak too soon at the 1 or 2 year mark when they could live 20+ years. Reminds me of crinoids where you hear about an individual who got a system that works for them but the other 99% don't find success or hit mysterious roadblocks trying to replicate that individual.
They're really cool animals and the day we crack the code on them I'd love to try and find success with them but as is rn, they need really big tanks, really deep sandbed, and food seems to still be a guessing game, its easy to at least replicate the water parameters they're caught in.