15 years or so back, my wife's father fell ill. She spent 6 months caring for him, I rarely saw her during this period. We had 4 young daughters, which were basically left to me to care for.
I had a fairly automated tank for the day, ATO direct to RO/DI filter, timers on the lights, etc. Beyond that, I fed 'em a couple times a week, 'bout all I had time for.
After 6 months of neglect, my beautiful reef was covered by watermelon mushrooms, which apparently really liked the dirty water. What wasn't covered by mushrooms was covered by C. Racemosa, which I had growing in my refugeum. Still had a few fishes, but that was it.
Tore it down, sold it off to my old reef club for pennies on the dollar, and was out of the hobby for a decade.
Sometimes, life intervenes in what we've got planned.