One eye being affected usually means an injury, but that would not be accompanied by a loss of appetite or skin peeling. Shedding is something a lion will do but the fading is more universal and if there is clouding of the eyes, it would be both eyes. Shedding can effect appetite. With one eye being cloudy and the peeling of the skin on the face, there could be some sort of infection, or one starting or ending. I have found with optimum water quality and a good diet, preferably with the live gut flora of live fish, most lions recover without any treatment. Using any meds with lions is tricky business, they do metabolize these chemicals differently and most times it turns out badly. Have you checked ammonia levels and are any other fish having an issue. You say you have had him for a few years, what is his diet and feeding schedule, has he gone off of feeding before. I've never found carbon to be issue, if so, this woul likely cause issue in both eyes.