First - not a "dumb" question at all. Quite a good one, in fact!
I'd guess that you're using water changes as part of your nutrient export plan (eg; getting rid of nitrates and such)? If so, then larger water changes will have more of an impact on this, of course.
You're also likely replacing trace nutrients at the same time. Depending upon how frequently you are doing water changes, you may or may not need to use more water for this purpose (if the nutrients aren't being significantly depleted at the 5gal volume, a 10gal change wouldn't help in this regard).
In either case - whether you're doing 5gal or 10gal - the key is to make sure you match your tank's salinity and temperature. If you do that, then it's unlikely that you'll do any harm to the tank. At the worst, you'll be "wasting" ~1/2cup of salt.
If you want to take a measured approach, I would suggest getting some test kits for various nutrients (and/or an ICP test). Find out where you are at in terms of your nutrient levels before your normal 5gal water change and after. If there's still more that needs doing (and the 5gal water change moved it in the right direction), then a 10gal change may make sense. But if the numbers are good (or didn't significantly move), then a larger water volume likely isn't needed.