I have a 75 Gallon which I'm running 1x Seachem Tidal 110,, 1 x Seachem Tidal 55, and a Aquaclear 70/refugium.
I was running two 110s but dropped to a 55 to make room for the Aquaclear. So far so good, they are super easy to clean.
Plus side to the Tidals are you don't have to worry about them starting up again after a power outage.