I’ve seen folks say this multiple times recently. I want to challenge that idea with
this post from Humblefish that both Coppersafe and Coper Power are totally safe to use with Prime. I have tested with Copper Power myself and had no issues. Perhaps you’re just referring to certain copper products?
As to the OP, sorry for your loss. When I started out I lost 3 fish to an ammonia spike in QT despite cycling with Turbostart. Now, I liberally use Prime when I make any changes to my tank (adding anything including CUC, fish, or big media changes). Just until I’ve monitored the ammonia long enough to ensure I’m good. For instance I got my current QT cycled and stable (just adding an old cycled sponge didn’t do it, still got a spike) then started going hypo when I found flukes. I never would have expected an ammonia spike but I got a big one and my fish didn’t care because of Prime (bio filter still hasn’t recovered 1 week in). Prime saved these fish twice. Another example...just adding some CUC members to my invert/coral QT also caused a spike. These are 20 gallon tanks with oversized filters and as much media as I can fit.
Given my experience I can’t help but recommend Prime and close ammonia monitoring with any tank changes especially small tanks.