I will confirm that I just loss a bunch of smooth skin sps when I dosed General Cure.. Last time I used it I had not issues but I only did one does.. this time to try and save my scribbled show male I followed the directions and did another after 48 hours... and bad luck and worse luck occurred... in summary maybe at low doses of Metro sps will be ok.. mine did not and as I write this I am losing more sps.. Wolverine, Prometheous and others to name a few... so aggravating... and the scribbled did not make it.. wasted away...