Agree the directions are a bit confusing on the Cupramine label.
Things to consider:
Your tank is probably not exactly 10 gallons (most are 9.5 + or -) and the dosage is
drops per 10.5 gallon. So that throws off the calculation of drops a bit.
Doing the two big doses as directed can be a bit harsh on some fish. So when I used to use Cupramine (highly recommend Copper Power instead) I would calculate the total numbers of drops to reach therapeutic range which is 0.40-0.50 ppm.
In my 10 gallon QT usually got to therapeutic around 35 or so drops, which I dosed a couple of drops AM, lunch, PM, each day until I reached therapeutic, according to my records, because of the slightly smaller size of the tank (I measured it and it is 9.4 gallons not including the HOB). This was for prophylactic treatment with no parasites in evidence. The smaller doses allow you to watch for copper sensitive fish.
Here's another thread where Humblefish answers the same question for another reefer. Hope this helps a bit.
Hey, Quick question. Cupramine directions say to redose every 48 hrs at 20 drops per 10.5 gallons. I do not mean to sound dumb here but do I take these directions literally and dose 20 drops per 10.5 gallons every 48 hrs to maintain therapeutic concentration? Just wanting to make sure...
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