My entire system water volume is 220g, part of which is a custom 25g acrylic tank just for water changes. It has one bulkhead on the input end and two on the output end. During normal operations it holds 21-22 gal of extra tank water circulating from the sump via its own pump and then back to the sump from output side. The second bulkhead on the output end is attached to a garden hose that runs out my basement to the back yard.
When I do a water change, I stop the pump to this tank, then open the valve on the drain hose to dump the old water out. When drained re-close that valve, fire up the RO/DI system, which after the flip of a couple valves on its output side now starts filling that WC tank back up. Depending on the time of year that takes 3.5/4 hours (unattended), then I add my salt, fire back up the power head and heater that live in that tank. Once clarity, salinity and temp are verified good, turn the WC tank pump back on and life proceeds until the next round. All in all maybe 30 min of actual effort over an afternoon, with zero lifting and carting around water buckets.
I can easily do these once a week to once a month (or more) depending on my or my tanks mood.