I've got 3 Radions over a 180g tank that was built last November. Prior to this, I've had T5s over a 55g and metal halide over a 20g. Here's my mini-review!
Pros:
Very easy to program from a Windows PC (or Mac running Parallels/VMWare with Windows)
- Software is a little confusing at first, but once you understand the control points/graph it's easy!
- Live preview as you edit the control points, and not just one color channel
- 30 second or 2 minute quick play through your entire day so you can see the transitions
- All three lights can be wirelessly grouped, only need to program one
Smooth transitions between colors and intensities - no more lights on/lights off like T5 or MH
Controls Vortech's in/out of night mode
No salt creep/salt attraction yet (7" off the water, in canopy, 2 full months)
Overall very quiet - fans make a little noise when the lights are at full power (my trio together are similar to a PS3 that's been on a while)
Amazing night caustics
Full control over the appearance and intensity of the light - not stuck with a particular color temperature
Can dial a little red into the evening mode to pop corals that don't fluoresce
Software updates add nice features to the programming tool and the light controller
Cons:
Price tag
USB port placement is odd, I ended up siliconing in a semi-permanent cable (in-canopy install)
Disco ball caustics during the day - the individual LEDs refract individually
Touch control placement on top is bad, fortunately rarely need to use these
Mounting can be a challenge - WWC made a custom rail mount for my setup
Limited control over the Vortechs - seems to be just in/out of night mode so far
Need a PC to program them - if you can't program them, you're missing out on too many features to justify the cost
A few more points...
I've tried "natural" mode and didn't care for it
I had a scare this weekend - found the tank dark mid-day.. forgot I'd programmed random clouds

I'm seeing good coral growth - all the corals seem to be enjoying this light
Overall, I'm exceedingly pleased with these lights. The built-in controller is powerful and very easy to program. They're quiet, flexible, run cool, and are energy efficient. They were very expensive, but I have no regrets - this aquarium build was about doing it right so as to not be replacing gear in the foreseeable future.
Check out my build thread in the large aquariums forum for photos of the mount and the USB cable mod.
--Shawn