Yes! I replicated the setup in this thread exactly -
https://www.reef2reef.com/threads/co2-scrubber-without-skimmer.918381/
It’s a BRS chamber, connected on one end to a 10W air pump (turned down to about 70%), and on the output end, I have a check valve to an air stone. The air stone sits in the middle chamber of my biocube and is vigorously aerating the water with Co2-deprived air 24/7. To maximize the life of the media, is is recommended to add a little water into the bottom of the media chamber. In my case, this would dry up in mere days and cause the media to be used up lightning fast. The RH in my apartment sits around 49-53%, and by putting the air pump into a plastic container that is humidified by a pool of water at the bottom, I am pumping in air with an RH of 75% which has lengthened the lifespan of the media. I also don’t have to worry about putting a teaspoon of water in the canister every couple of days. The air pump is sitting on a smaller plastic tupperware so the electronics arent sitting in a pool of water.
It is most ideal to hook this up to a skimmer air intake rather than an air pump and air stone, but with me using the cheap Biocube skimmer, it does not suck enough air and is too finicky to complicate IMO.
In my case, I had the water surface exchange and protein skimmer fighting against this scrubber since they were both aerating with high-co2 air. The biocube is covered so I don’t think the surface exchange is as big of an issue as it would be in a topless tank. In order to fight the Skimmer cancelling out the scrubber effect, I run the skimmer on a timer and it turns off a couple hours after lights out, and turns back on when lights ramp up so at my morning pH minimum, I’m only pumping in co2-reduced air which has prevented plummeting pH to the 7.6 range like was usual in my high-co2 environment.
While kinda complicated, this has kept my pH in a perfect range (7.9-8.3) for almost a month now.