I use Purigen on my 200 gallon system along with a large reef octopus skimmer. My water has been crystal clear since running it for about 3 months now. The Purigen actually has not even changed color yet. My skimmer is very efficient so it handles most of the bio load. Lately I have been noticing my lps corals not expanding as much, I believe this is from the chemical build up in the tank from the various toxins the corals produce. I have since been using carbon that I put in last week to clear the toxins up, I plan on running both medias going forward changing the carbon monthly.
A great media bag for the Purigen and carbon is sold by bulk reef supply. It's a drawstring small mesh nylon media bag and works excellent. I have not had good luck with seachems bag, always became brittle and broke. One great thing I have noticed is that the Purigen does not get the bacterial slime coat on it or the nylon media bag, even after weeks of use.
I do not run reactors just hang media bags by the tank return to sump, works very well as he returning water agitates the media in the bag.