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04-X to keep nitrates and phosphates down as well as dosing calcium and alkalinity. I have 400 gallons of total water volume and have been doing 10% every 2 weeks. I would see it depends on what your water quality is like with regards to the frequency for water changes. Some people do once a week or every two weeks. Some people do once a month.
10% of total water volumn is what i do once a week. Also water changes replenish trace element that we don't test for. Unless you dosing trace elements.

