The standard waste ratio is 4:1. If you are using softened water and have lower than normal TDS (the national average is around 250) then you may be able to reduce that to 3:1 or in rare cases 2:1.
Really though its not as expensive and you would think since it only wastes while you are making water. Say you make 100 gallons a month you waste 400 gallons. Water around here costs about $3.00 a thousand gallons and the sewer charge is similar so say that 500 gallons cost me ($3+$3/2 = $3.00) $3.00. 100/$3 = about 3 cents a treated gallon. Add in the cost of replacement sediment and carbon block filters every 6 months or so and DI resin and its more like a nickel or a little more per treated gallon.
The brine or waste isn't really wasted, its not gone, it gets sent to the sanitary sewer, treated and recharged back in the ground or used to water parks, golf courses or to fill a stream or lake. It gets recycled over and over.