The answer is either Never, or Four times a day, depending on your definition of blowing out...
I have a pair of Tunze 6105's connected to my Apex. Normally, they run a 1 minute ramp up, 25 - 40%, inverse, meaning one is ramping down while the other is ramping up, then they swap.
At 6am, Noon, 6PM, and Midnight, I kick both 6105's up to 100% power for 2 minutes. Really moves some water... Each is rated at 3400 GPH, with both running full out, there isn't anything settling in my tank. In fact, I've had to glue down my frag rack

Fish seem to have gotten used to it, though they freaked out a bit at first. Don't seem to mind anymore.
Nothing there to manually blow out