I've been doing saltwater for about 40 years, from UG filters to the present. I had a nice reef tank going in the 90s, with real live rock, softies, LPS and some easy SPS...dosed Kalk, had a HOB skimmer and never had any major issues and only broke it down when I moved.
Had a nice 40 gal reef tank in the 2000's for about 6-7 years...changed a little water about every few years, had live rock, softies, lps and some easy SPS. Only a good HOB skimmer with no other filtration or export. The only thing that died were the xenia since the tank would naturally denitrate itself. Only broke down when I moved (need to stop moving).
Now that I have some money, started up a nicer reefer 250 6 months ago with all good equipment, expecting better success. Just a Chaeto fuge and good skimmer. Started with dry rock, went through the cycle well, accumulated a fairly heavy bioload of fish, battled dinos since phosphates were always dead 0. Battled ich with Chloroquine Phosphate (which did kill the dinos). Battled algae since CP boosted Phosphates through the roof. Got a good CUC (urchins, turbo, sm Kole tang) and everything got settled and levels good. But I still hated the sterility and lack of diversity when I pulled out my flashlight at night...few creep crawlies. And the battles, while not abnormal for a new tank, were far worse than I've had since I started with established cured LR in the past.
Decided to get some uncured LR from KP aquatics...awesome stuff. Had a lot of sponges, coralline, brittle stars and stuff and had only a beach smell. I cured it for about 2 weeks in my QT with lights on to keep everything I could alive and removed stuff that didn't make it (sponges) and a pistol shrimp hitchhiker, doing a lot of water changes to keep ammonia levels low. After 2 weeks, they were 100% good to go with zero ammonia.
Subbed about 1/3 of my dry rock out with the newly cured LR and things settled in very quickly. I got my creepy crawlies back. Interestingly, the live rock has stayed algae free, while the dry rock still is green and the CUC concentrates on it.
I'm at a stable point (at least for now) with Nitrates and phosphates staying low but not zero. Now, finally, just starting out with a clam and some LPS which seem to be doing well. If things stay stable for a few months, will go into the SPS land.
If I were to start again, I'd start with all live rock like I did with my other tanks. Using dry rock, for the first few years keeping everything steady is like balancing a ball bearing on a beach ball. It can certainly be done, but takes a lot of perseverance and some luck. LR reefing is more like keeping a ball bearing on a flat board...still not easy, but a lot more forgiving due to the diversity. So far, hitchhikers haven't been an issue.
I frankly get much joy out of seeing the pods and worms and things at night, knowing I'm keeping a good analog of nature. If something dies or I overfeed, it will be taken care of quickly and efficiently.