That's a pretty broad question, however I've tried all kinds of setups and done few rebuilds. I've learned over 2 decades that key to successs is patience, stability (no tinkering) and hands and Coral Food additives out of tank. All setups will work if run properly (Proper monitoring and maintenance) I've learned after many slap on the hands, that adding magic potions may work for the short term but in the long run it's a ticking timebomb for a cyano, or algae outbreak.
My 110G SPS-only tank is tech-complex in the respect of total automation. That's because SPS are unforgiving for water quality, and stability.
However a year ago I setup a very simple
35 gallon tank (below) a bit differently. I wanted to start a frag tank hooked into the main tank but plumbing was impossible to achieve. So I went standalone. I started with a bunch of hand me down rocks and not so heathy pale corals (Hand me down).
I added Couple of fish, CUC, lots of live rock, and corals. Daily automated water changes (2%), a 2 Part Doser for Alk/Calc.
A mini Algae Scrubber Chamber. (Black box-Left corner) Nothing else except ATO. No skimmer.
I've tried this before
without fish and it failed each time. Adding "fish poo" = "Natural Coral food" was the secret potion for thriving corals.
A year later. Nutrients was feeding 2 Fish once a day frozen food.
Doesn't take much food to get corals to grow. The Planned Frag tank turn into a mini reef unexpectanly.
On other tanks, I've used Reef Roids and a ton of other things (amino's) to boost my corals growth and colors. I stopped all additives since it always ended up giving problems. I prefer to feed fish and fish feed the corals. No poluting water. If you do use Reef Roids don't broadcast feed like I did (lazy). Best way is to target feed each coral a small amount while tank flow is turned off.
If you want simple. Go Natural in your tank and equipment. Little bit of automation make your life easier. Adding an Algae was the best thing I ever did for my tanks. My algae scrubber doesn't grow Hair Algae like others do. It's just a chamber that grows Cheato from flow thru return water. This is my monthly harvest on the 110G tank.
For the SPS tank I still use GFO. RowaPhos. Small amount, but changed every two week. Keeps phosphates on target.
When I learned simple worked for my Frag Tank, I applied the exact same approach to my SPS tank, and within a year it turned into this.
From this..
Simple and stable works best. TOOK me 25 years to figure it out.
Hope I answer at least part of your question.