I had Uronema in a couple of wrasses and I contacted my favorite LFS and they were in complete denial. The problem is most LFS run meds at sub therapeutic levels to keep these parasites from taking over, Then you bring the fish home and place it in non medicated water and it is taken over. I was fortunate that mine developed Uronema in QT so that was an easy clean up.
Any remaining fish if you want to be sure should go to QT and be treated with double dose of metro for 14 days. This really is a crap shoot you could in theory never see it again with your remaining fish but when you add a new fish it could show its head again. Unfortunately yes the only way to eradicate Uronema completely from your DT is a complete tear down, sterilization, and start over (including live rock). Hopefully from here forward you will utilize a QT to avoid these problems in the future.
Here is a write up on Uronema
https://www.reef2reef.com/threads/uronema-marinum.247940/
One thing I’ll share is that copper does virtually nothing for uronema. We’ve had it take hold even in fully therapeutic copper. Metroplex was how we treated it. I agree with the diagnosis, by the way.
I didn’t used to take this disease seriously because it seemed to only impact chromis, some anthias, angels, and some butterflies. But now more angels (especially dwarf), many other fish including wrasse are getting it.
I’ve never worried about it in my tank because my fish were healthy enough it didn’t cause an issue. What I don’t know is if it’s somehow more virulent now or if the overall condition of the fish we receive these days is less and thus it takes hold. Or both, perhaps.
So I don’t know how I feel. I still suspect that after quarantine and treatment, a fat, healthy fish added to a display tank that “once had” (still does almost certainly) uronema may be fine. But chromis are probably still a large risk, followed by anthias, some butterflies, and dwarf angels (in that order).
The only thing I’ve not seen uronema seem to harm recently was tangs. They seemed unaffected as everyone dropped dead before we figured out what was going on. Once you see uronema and diagnose it on a fish it’s almost always too late for that fish.
I can’t stress enough how important treating and proper quarantine procedures are these days. I can’t speak to exactly why but disease is rampant and fish health seems considerably worse than it was a few years ago, and even ten years ago for certain.
So your options are to nuke everything with bleach and start over, or hope that healthy fish won’t be affected going forward. Both require quarantining from here out for best results.
Good luck, sorry for your loss
