thats too subjective to answer.
better question: for those who will never require nor use nor buy it, how are they building reefs? since its an optional item, its nice to know how to de option it, and spend the money on a frag
the way to never need it is to clean your tank periodically vs letting detritus build up inside.
consider if you want a sandbed or not, no sandbed means its easier to clean up since its on glass and the waste can be removed.
sandbed means you need to clean it occasionally to keep it in control if you want the best chance of success.
you should arrange rocks not as a giant inaccessible stack, that builds up waste, but arrange your system in a way that every inch of it can be accessed for cleaning, just occasionally, if required.
Ergo: use of that item doesnt mean your tank left uncleaned will work and the microbe lift fixes it for you without work. Those dosers merely give people who reef by storage (and are under invasion accordingly) a chance at fixing things, by avoiding more work.
Even when used as basic care replacement, this or any bottle bac doser attains the desired results 4% of the time.
*some are using it for dinos battles or bad cyano not related to waste, thats legit*
96% they still must clean, eventually.