Strong lighting/flow is a definite. Medicine/QT can be avoided though if you purchase one that's been treated. I did not treat either of these anemones. The multi color came from Galactic Coral, I'm not sure if they treated first or not. It was the only anemone going in my tank at the time and looked healthy so I didn't worry about treating. The blue one I got from Blue Kai Aquatics and that one I know was treated before I purchased. The pre treated ones can get expensive, but imo not a bad price for something that can out live you and also one of the more elusive species in the hobby.