She's has been in the hospital tank with the triple antibiotics, one dip in Rid Ich and 2 courses of prazi since March 12... so I guess we have tried it all. Will start water changes and move her back to the biocube and let her enjoy her domain as long as possible. She and her mate are 4 now, hope perhaps it will resolve on its own. Will update if anything changes - and if we lose her I hope to talk my vet into a necropsy so we can at least know what the heck this was.
Thanks so much for all the help and ideas! If anyone runs across a similar situation that was successfully resolved, please let me know.