Thank you for your reply. You are correct. The fish that had the disease were newly purchased. I immediately put them in the 60 gallon QT with my other fish (3x clowns, 4x damsels 2x cardinal, 3x fire fish, and a dwarf angel). The QT has been established over a year as it was an old tank now turned into a QT with live rock as I'm currently cycling a larger new tank. The disease killed the lyretails and the first wrasse within a week of their arrival. Then the second wrasse died a few days later (seen in pic). So I think it came with them. The water parameters seems fine and the QT has established bacteria. Here is a picture of my clown now that developing spots. I've been dosing kanaplex since Sunday and metroplex since Tuesday. And I just dosed rally pro last night. But nothing seems to work. I also put an airstone in the QT for oxygen. I don't know what to do next. Any advise would be greatly appreciated.