Prazi/fluke question

[Schulks]

I'm treating a pair of clowns with prazi and some antibiotics. Day 1 and day 7 are prazi days and every 3 days I am redosing the antibiotics with a water change. Does the water change effect the prazi treatment?

Does prazi need to be in the water column the entire treatment or only for the initial days it is dosed?

Thanks for your help!

 

[Sharkbait19]

Praziquantel breaks down after a few days. The repeated dosages act as a way to catch any eggs not hit the first time(s).

 

[besskurz]

Hi I'm not very used to use prazipro, but this post might be helpful to you:

EMERGENCY - Prazipro water changing?

I have been treating my 60 gal with prazipro , im on the 5 day mark (out of said 7) and i did a water change, is it necessary to retreat the water with prazipro oncemore? If so how much should i add? I also read that doing a 14 day treatment with another waterchange is necessary…. but basic...

www.reef2reef.com

 

[Schulks]

Praziquantel breaks down after a few days. The repeated dosages act as a way to catch any eggs not hit the first time(s).

I guess I was worried if they would mature and lay more eggs without prazi in the water. Your first sentence answers that though.

 

[Sharkbait19]

I guess I was worried if they would mature and lay more eggs without prazi in the water. Your first sentence answers that though.

It can happen, like any medication it isn’t perfect and some will survive. The repeated doses will ensure all flukes are caught. Dosing 9 days apart interrupts their life cycle the best.

 

[Schulks]

It can happen, like any medication it isn’t perfect and some will survive. The repeated doses will ensure all flukes are caught. Dosing 9 days apart interrupts their life cycle the best.

I have actually already dosed prazi twice. Day 1 and day 3. Tomorrow will be day 6 and I will need to water change and do antibiotics again. Another prazi dose here is useless right? I can just wait another 3 days for the final antibiotic dose and redose prazi then.

 

[Sharkbait19]

Yes, dosing should be 9 days apart.
No need to do them too close together.

 

[vetteguy53081]

I'm treating a pair of clowns with prazi and some antibiotics. Day 1 and day 7 are prazi days and every 3 days I am redosing the antibiotics with a water change. Does the water change effect the prazi treatment?

Does prazi need to be in the water column the entire treatment or only for the initial days it is dosed?

Thanks for your help!

Incorrect recommendation for prazi
You want to remove carbon and do an initial dose known as interval and allow that dose to work for 8 days. Day 9, do a water change then apply one more interval for 8 days then add carbon. Increase oxygen with air stone as Prazi slightly reduces both oxygen and appetite. If changing water, you are interrupting the dosage as there is no way to measure loss of agent other than to add a couple of M/L
Twice a day is a No.

 

[Schulks]

Incorrect recommendation for prazi
You want to remove carbon and do an initial dose known as interval and allow that dose to work for 8 days. Day 9, do a water change then apply one more interval for 8 days then add carbon. Increase oxygen with airstone as Prazi slightly reduces both oxygen and appetite

So I need the prazi in the water for the entire treatment duration? I can't do a water change in the middle even if it were for water parameter reasons?

I didn't dose prazi twice in one day. I dosed prazi day 1 and then day 3 I did about a 50% water change and dosed again. The only reason I did that dose is because I was changing water and redosing my nitrofurizone/kanaplex.

 

[Schulks]

Incorrect recommendation for prazi
You want to remove carbon and do an initial dose known as interval and allow that dose to work for 8 days. Day 9, do a water change then apply one more interval for 8 days then add carbon. Increase oxygen with air stone as Prazi slightly reduces both oxygen and appetite. If changing water, you are interrupting the dosage as there is no way to measure loss of agent other than to add a couple of M/L
Twice a day is a No.

I thought I read from a decent source I could use these antibiotics with prazi but now I can't find that source and I'm reading the opposite online. I am probably just going to quit the prazi treatment and stick with antibiotics.

Though the fish have been behaving fine, eating well and active. I've already done about 5 days of prazi, nitrofurizone/kanaplex in water, and feeding metroplex.