That said, there are basically three camps that I’ve seen with QT:
-Full, medicated QT (the timeframe for this can vary, but Jay Hemdal’s 2023 protocols suggests 64 days); this is likely the most stressful option, but the thought for this is basically that disease can’t wipe out your tank if it isn’t in your tank. Some people believe this weakens a fish’s immune system and may lead to them dying relatively young.
-Observational QT (I generally see this from reefers in places where it’s harder to get fish meds); this option is probably still stressful for the fish, but it seems to be more about avoiding particularly deadly diseases (such as velvet) or knowing in advance what you’re allowing into the tank. This method carries a lot of the same risks as no-QT (see below), but it can give a heads-up about issues new fish may have/introduce.
-No QT; this avoids the stress of being moved between tanks, but I feel like Paul B’s comment above is a pretty accurate description here. The thought here is that a healthy fish with a healthy immune system won’t die except from old age. Basically, this method can work if you’re able to provide good water, good food, and a good environment for the fish. Most newcomers to the hobby are probably not capable of that when they start, and when the fish isn’t healthy/is too stressed (such as because of inadequate water, food, or environment), them any diseases they’re carrying flare up and can take them out (hence why the disease forum here is full of no-QT tanks getting wiped out by diseases). This method does carry the risks that 1) a deadly disease like velvet may come in and wipe some or all of the fish in the tank out unexpectedly and 2) if a stressful event (such as a bacterial bloom, for example) happens unexpectedly, you may face a disease outbreak in the tank at the same time. Jay Hemdal has some posts about other potential weaknesses of this method here on R2R too, but these are the most important in my mind for most people to be aware of.
So, for most people a properly done, full, medicated QT is probably the safer route to go with when just starting out - honestly, this is why I’m personally a fan of pre-QT vendors, as they have a pretty good track record of delivering disease-free fish (meaning that sub-optimal care like the average newcomer is likely to unintentionally give the fish is less likely to kill it), and it’s hassle-free for the buyer.
Again, all of these methods when done properly can work, and they all have some pros and cons, but those are my two cents on the matter.