Ok I have both the Red Sea, D-D and Apex (salinity probe) and they all read differently if you let them.
When I first started out I spoke with Kevin at Red Sea about the Refractometer and basically it is extremely sensitive and needs to be calibrated before each use, as per the instructions. I find it particularly sensitive to temperature.
I purchased the D-D after I got Apex as the salinity probe was all over the place compared with my trusty Red Sea Refractometer, so I thought I had better check everything. The problem with the D-D is the scale is very difficult to read, for me anyway.
So, in summary my preference is the Red Sea Refractometer and here is what I do.
I calibrate with 0 RODI (I haven’t found any noticeable/significant difference using the 35ppm fluid and I have both). I leave RODI on the glass for 15 seconds to adjust temperature and then adjust the scale to calibrate.
I then wipe (with my shirt of course! Lol) and add the saltwater, leave for 15 seconds, and then take the reading. Done.
The calibration takes a few seconds once you get used to it.
I now calibrate Apex (I use tank water when Im happy it’s 35ppm instead of Neptune’s calibration fluid which causes wild readings!) according to my Red Rea Refractometer and it’s all line, and on the basis my system thrives, it must be ok.