To clarify: What I meant by treating & isolating is it would be better to setup another QT for the sick anthias and treat in there. So your other fish are not being exposed to antibiotics unnecessarily (although if the infection spreads, your other fish will require treatment). Exposing a fish with a bacterial infection to antibiotics for just one hour isn't going to do much good. Long-term exposure is usually required, so the fish's skin can absorb the medication. Alternatively, you can soak antibiotics in the fish's food and when they ingest it, it gets absorbed that way (Kanaplex works particularly well for this). But the problem is ensuring the fish is eating it (and in sufficient quantities). Dosing it directly into the water column forces them to "take their medicine" whether they want it or not. :xd:
I've always dosed as per the directions on the Furan-2 box (85mg) and have had pretty good results. I prefer to underdose nitrofurazone, as that particular antibiotic can have nasty side effects if overdosed. You can also safely combine Furan-2+Kanaplex+metronidazole for an even wider spectrum of treatment, and lately I've been finding that mixture to be extremely effective (kudos to someone on RC for telling me about it).
The main thing you want to do when treating with antibiotics (no matter which one) is provide plenty of gas exchange. Antibiotics are notorious for depleting the water of O2 and IMO, this why so many people claim to lose fish while treating.