Assuming it does not have organics in it (a few like Reef Crystals and Tropic Marin Bioactif do), then it can be stored a long time unstirred and unheated. I store mine for more than a month. Organics in the mix can degrade and potentially grow bacteria.
Some mixes with high alk and pH may suffer precipitation of some calcium carbonate on heaters or pumps if you keep them going, but in general it won't typically drive levels excessively low (but alk may be detectably lower than when first made). A lot of folks might actually prefer the lower alk, and some people add acid to achieve that. The calcium drop will be minimal.